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Thread: Merck to Withdraw Vioxx Because of Heart Risks

  1. #31
    Senior Hostboard Member reason's Avatar
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    Actually, I withdraw from this discussion. I can't take it. Sometimes it's better to slowly...back...away... [img]eek.gif[/img]

  2. #32
    Inactive Member Dulcinea's Avatar
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    How do you respond to the criticism that drug companies spend more money on marketing than they do on research and development?
    <font size="2" face="Verdana, Helvetica, sans-serif">I cannot justify that. But I believe there is much less of that going on than there used to be, and much of what had been going on was the vicious circle of the competition is doing it, we had better at least match it. So you go from giving them a pen that has the drug name written on it so they have it in front of them when writing prescriptions, and educational materials like wall charts etc. to bigger and bigger gifts until someone says "enough".


    And how much does litigation play into the cost of drugs in the United States?
    <font size="2" face="Verdana, Helvetica, sans-serif">I don't know the numbers. I am sure it adds to the cost, (and everyone knows what venues return the biggest court awards), and all the clinical trial results are scrutinized very closely by both the government and the companies involved. Nobody wants people to die, and there are different levels of "allowable" side effects related to what is being treated - you can allow more serious side effects for something treating a life-threatening disease such as cancer than you would allow for something treating a headache. But at any rate, the companies (like Merck) will pull drugs as soon as the cumulative evidence shows this sort of correlation. The numbers of people taking Vioxx for several years could not possibly have been matched by clinical trials, and if this did not show up in clinical trials, that should mitigate Merck's exposure (but, of course, it might not).

    I have also argued that we here in the United States "compensate" socialized medicine around the world. Because governments control prices in places like Canada and France, and a host of other countries, the citizens of this country are left to pick up the tab while they get the benefit of lower prices (albeit with fewer available drugs).

    There are huge fixed costs associated with drug development. We in the US are left to cover those costs. The rest of the world's revenues are gravy.
    <font size="2" face="Verdana, Helvetica, sans-serif">You are preaching to the choir here. The alternative is to not sell to these other countries at their governments' fixed prices. Usually those prices ARE above manufacturing costs even though they will not help much to recoup the R&D investment, so Pharma might as well play by their rules. But many companies have begun to restrict the sales of drugs to countries such as Canada to levels that are thought to be the usage in that country. If they export some obtained at their price structure, there will not be enough for Canadians. We are already seeing 3rd world and counterfeit medicine showing up in Canada, not much but it looks like a trend.

    So, if we only sold to the US only the US would bear the cost of development and the less scrupulous nations would read the patents and make the stuff anyway. This way Pharma gets just a little profit outside the US, and the drugs they get are almost certainly safer.

    Tariffs and constraits on free trade suck.
    [img]graemlins/thumbs_down.gif[/img]

  3. #33
    Inactive Member Dulcinea's Avatar
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    But isn't one of the major problems the big pharmaceutical companies are facing is the lack of big, blockbuster drugs in the pipeline?

    One of the reasons Merck's stock took such a big hit with Vioxx is not only because it was huge revenue producer. Merck's pipeline has run dry of drugs to replace it, and that is the issue.

    As patents run out on the old war horse drugs that made the Mercks and Schering Ploughs their cash, there's less to replace them - even without these political pressures.
    <font size="2" face="Verdana, Helvetica, sans-serif">There was "nothing in the pipeline" until every blockbuster drug came along. The new stuff is harder to find than the old stuff, but the tools are better too. We aren't done with the new stuff that'll knock your socks off with great financials.

    ....you'll see more of the majors buying up smaller companies who have a blockbuster drug or two.
    So instead of R&D by the majors, they'll let the small guys do it, then buy them up at a premium
    <font size="2" face="Verdana, Helvetica, sans-serif">Sure, let the failures go into bankruptcy and those who roll the dice and win get rewarded. It's more cost-effective than bearing the costs of your own failures, spreads that cost out over the American public more invisibly than by raising the costs of drugs.

  4. #34
    Inactive Member Dulcinea's Avatar
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    Back to the original story.....

    Get your million dollars for taking Vioxx

    One of my favorite parts:
    There are still places selling Vioxx after the recall, you can find them online. Merck is still 100% fully responsible for any side effect. If you purchase Vioxx now, not only you can sue Merck, you can also sue the pharmacy store for selling recalled products.
    <font size="2" face="Verdana, Helvetica, sans-serif"><font size="4">Lew, get your self to this thread!</font>

  5. #35
    Senior Hostboard Member reason's Avatar
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    Originally posted by Aurora Leigh:
    Back to the original story.....

    Get your million dollars for taking Vioxx

    One of my favorite parts: </font><blockquote><font size="1" face="Verdana, Helvetica, sans-serif">quote:</font><hr /><font size="2" face="Verdana, Helvetica, sans-serif"> There are still places selling Vioxx after the recall, you can find them online. Merck is still 100% fully responsible for any side effect. If you purchase Vioxx now, not only you can sue Merck, you can also sue the pharmacy store for selling recalled products.
    <font size="2" face="Verdana, Helvetica, sans-serif"><font size="4">Lew, get your self to this thread!</font></font><hr /></blockquote><font size="2" face="Verdana, Helvetica, sans-serif">Where do I buy this miracle drug? Early retirement, HERE I COME!

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